Depth-targeted energy delivery deep inside scattering media

Optical focusing deep inside dynamic scattering media with near-infrared time-reversed ultrasonically encoded (TRUE) light.

Focusing light deep inside living tissue has not been achieved despite its promise to play a central role in biomedical imaging, optical manipulation and therapy. To address this challenge, internal-guide-star-based wavefront engineering techniques--for example, time-reversed ultrasonically encoded (TRUE) optical focusing--were developed. The speeds of these techniques, however, were limited to...

On high energy scattering inside gravitational backgrounds

We analyze the high energy scattering inside gravitational backgrounds using ’t Hooft’s formalism. The scattering is equivalent to geodesic shifts accross Aichelburg-Sexl waves inside the gravitational backgrounds. We find solutions for A-S waves inside various backgrounds and analyze them.

The energy blocker inside the power house: Mitochondria targeted delivery of 3-bromopyruvate.

A key hallmark of many aggressive cancers is accelerated glucose metabolism. The enzymes that catalyze the first step of glucose metabolism are hexokinases. High levels of hexokinase 2 (HK2) are found in cancer cells, but only in a limited number of normal tissues. Metabolic reprogramming of cancer cells using the energy blocker, 3-bromopyruvate (3-BP) that inhibits HK2 has the potential to pro...

Targeted Content Delivery for Social Media Content

Spotting contextually relevant keywords is fundamental to effective content suggestions on the Web. In this regard, misspellings, entity variations and off-topic discussions in content from Social Media pose unique challenges. Here, we present an algorithm that assists content delivery systems by identifying contextually relevant keywords and eliminating off-topic keywords. A preliminary user s...

Advances in Targeted Drug Delivery